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The principal cytochrome P450 isoenzyme involved appears being CYP2E1, with CYP1A2 and CYP3A4 as added pathways. Around 85% of the oral dose appears from the urine in just 24 several hours of administration, most as the glucuronide conjugate, with modest quantities of other conjugates and unchanged drug (see OVERDOSAGE) for toxicity info.Individual

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